Interpretation of renal biomarkers in dogs and cats – when do we need an SDMA?

Speaker: Tim Williams

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Interpretation of renal biomarkers in dogs and cats – when do we need an SDMA?


The lecture will review how to interpret renal biomarkers correctly in dogs and cats. the The factors affecting serum urea and creatinine concentrations and indications for measurement of serum SDMA concentrations will be discussed. Then the lecture will cover the interpretation of azotaemia and how to distinguish pre-renal, renal and post renal causes (including the interpretation of urine specific gravity). Finally we will cover the pathogenesis and correct interpretation of proteinuria.

 

Learning objectives

  1. Understand the causes of low and high serum urea and creatinine concentrations and the limitations of these analytes as biomarkers of renal function
  2. Know how to interpret azotaemia in a clinical patient and differentiate between the causes of azotaemia
  3. Identify the circumstances in which measurement of SDMA is warranted.
  4. Know how to interpret urine specific gravity, and the factors that influence urine specific gravity.
  5. Understand the pathogenesis of proteinuria and it’s interpretation.